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Thus, toxic metabolites of VPA can lead to an increase in the severity of neurological diseases and mental disorders [19], congenital malformations in the fetus [20], dysfunction of the neuroendocrine system [21], and impaired hematopoiesis [22]

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Sensitivity analyses further confirmed results robustness, except for UA hospitalization

Rationale, design and baseline characteristics of REMODEL, a mechanism-of-action trial with semaglutide in people with type 2 diabetes and chronic kidney disease NDT Authors David Z I Cherney, Nicolas Belmar, Petter Bjornstad, Milenta M Chacko, Thomas P Gunnarsso, Jeffrey B Hodgin, Matthias Kretzler, Menno Pruijm, Philip A Schytz, Katherine R Tuttle Background Type 2 diabetes (T2D) is the leading cause of chronic kidney disease (CKD) and kidney failure globally

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